Company Filing History:

8 out of 600

Baylor College of Medicine

patents

2 out of 3,682

The Johns Hopkins University

patents

3 out of 832,680

Other

patents

where one patent can have more than one assignee

Years Active: 1998-2010

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11 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 7829333 - Modulation of hedgehog-mediated signaling pathway (2010-11-09),

2. 7049090 - Modulation of hedgehog-mediated signaling pathway (2006-05-23),

3. 6733971 - Method for identifying an agent that affects a hedgehog signaling pathway (2004-05-11),

4. 6599698 - Mutated steroid hormone receptors, methods for their use and molecular switch for gene therapy (2003-07-29),

5. 6416998 - Plasmid encoding a modified steroid hormone (2002-07-09),

6. 6380373 - Steroid receptor coactivator compositions and methods of use (2002-04-30),

7. 6277566 - Method for identifying a hedgehog-mediated phosphorylation state dependent transcription factor (2001-08-21),

8. 5935934 - Mutated steroid hormone receptors, methods for their use and molecular (1999-08-10),

9. 5874534 - Mutated steroid hormone receptors, methods for their use and molecular (1999-02-23),

10. 5849477 - Assays of coup transcription factor interactions in mammalian systems (1998-12-15),

11. 5759785 - Method of identifying hormone antagonists and agonists (1998-06-02),

Title: Inventor Ming-Jer Tsai: A Pioneer in Hedgehog-Mediated Signaling Pathway Innovations

Introduction

Ming-Jer Tsai, based in Houston, TX, is an innovative inventor recognized for his significant contributions to biomedical research. With a remarkable portfolio of 11 patents, Tsai has been at the forefront of research involving critical biological pathways.

Latest Patents

Among Ming-Jer Tsai's latest patents is a groundbreaking invention related to the modulation of the hedgehog-mediated signaling pathway. This invention provides insights into transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation through phosphatases. His invention offers hedgehog response elements (HRE) that interact with dephosphorylated transcription factors and includes methods for identifying compounds that act as phosphatase inhibitors. Additionally, the patent outlines novel methods for treating tumors in subjects by modulating the phosphorylation of these transcription factors.

Career Highlights

Ming-Jer Tsai has made influential strides throughout his career, particularly during his tenure at Baylor College of Medicine. His research has contributed to the advancement of understanding cellular signaling pathways, which are vital in cancer biology and treatment.

Collaborations

Throughout his career, Tsai has collaborated with prominent scientists, including Bert W O'Malley and Sophia Yang Tsai. These cooperative efforts have not only enriched his research but also fostered innovative solutions that may impact therapeutic strategies.

Conclusion

With his dedication to innovation and a strong track record of patents, Ming-Jer Tsai has established himself as a notable inventor. His work in modulating the hedgehog signaling pathway opens up new frontiers in medical treatments and solidifies his reputation in the scientific community.

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