Location History:
- Lakewood, OH (US) (2000)
- Mayfield Heights, OH (US) (2005 - 2014)
- Cleveland Heights, OH (US) (2016)
- Cleveland, OH (US) (2023)
Company Filing History:
Years Active: 2000-2023
Title: Miklos Gratzl: Innovator in Microfluidic Technology
Introduction
Miklos Gratzl is a prominent inventor based in Mayfield Heights, Ohio, known for his significant contributions to the field of microfluidics. With a total of eight patents to his name, Gratzl has made remarkable advancements in enzyme diagnostics and multiparametric analysis.
Latest Patents
One of his latest inventions is the "Microfluidic pH-stat for point of care (POC) enzyme diagnostics." This innovative device features a specially designed slide and portable apparatus that facilitates enzyme diagnostics at the point of care. The slide incorporates a microchamber and a substrate for the enzyme being tested. The substrate is homogenized with the sample in the microchamber to create a test volume. The microchamber is equipped with a working microelectrode that injects current to split water in the test volume, generating hydrogen ions and/or hydroxide ions. Additionally, a micro-pH-electrode measures the pH of the test volume, while a reference microelectrode is also included. The device's processor adjusts the injected current based on the pH, allowing for the determination of enzyme activity based on the amount of current adjusted.
Another notable patent is the "Multicellular system and method for multiparametric analysis." This system features a substrate with a major surface that includes at least one radial electrode array, upon which a three-dimensional (3D) cell aggregate is disposed. The 3D cell aggregate has a longitudinal surface that partially covers one or more electrodes of the radial electrode array, enabling advanced multiparametric analysis.
Career Highlights
Miklos Gratzl is affiliated with Case Western Reserve University, where he continues to push the boundaries of research and innovation in his field. His work has garnered attention for its potential applications in medical diagnostics and research.
Collaborations
Gratzl has collaborated with notable colleagues, including George Rozakis and Sumitha Nair, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Miklos Gratzl's contributions to microfluidic technology and enzyme diagnostics exemplify the impact of innovative thinking in the scientific community. His patents reflect a commitment to advancing healthcare solutions through technology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.