This inventor holds 3 USPTO granted patents. Top assignee: Shionogi Company Limited. Active years: 1976-1984.
Location History:
- Ikeda, JA (1976)
- Osaka, JP (1984)
Company Filing History:
Years Active: 1976-1984
Title: The Innovations of Mikao Mayama
Introduction
Mikao Mayama is a notable inventor based in Ikeda, Japan. He has made significant contributions to the field of antibiotics, holding a total of 3 patents. His work focuses on developing new antibiotics that are effective against various pathogenic microorganisms.
Latest Patents
Mikao Mayama's latest patents include Antibiotics PA-41746-B and C, which are new antibiotics exhibiting .beta.-lactamase inhibitory activity. These compounds are characterized by the formula wherein R is carboxymethylsulfinyl (PA-41746-B) or formylsulfinyl (PA-41746-C). They are useful as medicaments, veterinary drugs, and disinfectants for inhibiting the growth of both gram-positive and gram-negative pathogenic microorganisms. The process for preparing these antibiotics involves cultivating Streptomyces pluracidomyceticus in a suitable medium and isolating PA-41746-B and/or PA-41746-C from the culture broth. Additionally, he has developed antibiotic siomycin A derivatives produced by the reaction of siomycin A with a dicarboxylic acid. These derivatives exhibit excellent solubility characteristics compared to siomycin A and are also useful as medicaments.
Career Highlights
Mikao Mayama is associated with Shionogi Company Limited, where he continues to innovate in the field of antibiotic research. His work has been instrumental in advancing the development of new therapeutic agents that address critical health challenges.
Collaborations
Mikao has collaborated with notable colleagues such as Shinzo Matsuura and Kouichi Matsumoto, contributing to the advancement of antibiotic research and development.
Conclusion
Mikao Mayama's contributions to antibiotic innovation highlight his commitment to improving healthcare through scientific research. His patents reflect a dedication to developing effective treatments against harmful microorganisms.