Company Filing History:
Years Active: 2000-2006
Title: Michelle A Schmidt: Innovator in Protease Inhibition
Introduction
Michelle A Schmidt is a notable inventor based in Belleville, IL (US). She has made significant contributions to the field of protease inhibitors, holding a total of 3 patents. Her work focuses on developing compounds that can effectively inhibit specific protease activities, which are crucial in various pathological conditions.
Latest Patents
One of her latest patents is titled "Piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors." This invention is directed towards proteinase inhibitors, particularly those that inhibit matrix metalloproteinase (MMP) activity and aggrecanase activity. The hydroxamic acids she developed correspond to a specific structural formula and include salts of these compounds. Additionally, her invention encompasses compositions of these hydroxamic acids, intermediates for their synthesis, and methods for treating conditions associated with MMP and aggrecanase activity.
Another significant patent involves "Labeled neurotensin derivatives." This patent discloses peptide analogs of neurotensin that are resistant to enzymatic degradation while retaining high binding affinity for neurotensin receptors. The pharmaceutical compositions derived from these compounds are useful for both diagnostic and therapeutic purposes.
Career Highlights
Throughout her career, Michelle has worked with prominent companies such as Pharmacia Corporation and Biosynthema Inc. Her experience in these organizations has contributed to her expertise in the field of pharmaceutical innovations.
Collaborations
Michelle has collaborated with notable colleagues, including Ananthachari Srinivasan and Thomas E Barta. These collaborations have likely enhanced her research and development efforts in protease inhibitors.
Conclusion
Michelle A Schmidt is a pioneering inventor whose work in protease inhibitors has the potential to impact therapeutic approaches for various diseases. Her innovative patents and collaborations reflect her commitment to advancing medical science.