Location History:
- Avenel, NJ (US) (2010)
- Scotch Plains, NJ (US) (2007 - 2012)
Company Filing History:
Years Active: 2007-2012
Title: Michele Diegmann: Innovator in Bone Graft Technology
Introduction
Michele Diegmann is a notable inventor based in Scotch Plains, NJ (US). She has made significant contributions to the field of biomedical engineering, particularly in the development of advanced bone graft technologies. With a total of 3 patents to her name, Diegmann's work has the potential to enhance surgical outcomes and improve patient care.
Latest Patents
One of her latest patents is for a Non-glycerol stabilized bone graft. This innovation involves a demineralized bone matrix (DBM) or other matrix composition that has been stabilized by lowering the pH, reducing water content, adding water substitutes, and increasing the amount of deuterated water. This method aims to reduce the activity of endogenous degrading enzymes such as proteases. The hydrated form of the stabilized DBM composition can remain stable for up to a year at room temperature at acidic pH. Additionally, the acidified DBM compositions can be further stabilized by incorporating agents like deuterated water, water substitutes, polymers, protease inhibitors, glycerol, or hydrogels.
Another significant patent is for an Osteoimplant and method for making the same. This patent describes a method of manufacturing an osteoinductive osteoimplant, which includes demineralizing part or all of at least one surface of a monolithic section of cortical bone to a depth of at least about 100 microns. The method configures the monolithic section to create an osteoimplant with both demineralized and non-demineralized zones. Implants produced using this method demonstrate improved osteoinduction without clinically significant reductions in strength in critical regions.
Career Highlights
Michele Diegmann has worked with several prominent companies in the biomedical field, including Osteotech, Inc. and Warsaw Orthopedic, Inc. Her experience in these organizations has allowed her to develop and refine her innovative ideas, contributing to advancements in bone graft technology.
Collaborations
Throughout her career, Diegmann has collaborated with notable professionals in her field, including Jean T Edwards and Lawrence A Shimp. These collaborations have further enriched her work and expanded the impact of her inventions.
Conclusion
Michele Diegmann's contributions to the field of bone graft technology are significant and impactful.