Company Filing History:
Years Active: 2001-2003
Title: Michel Couder: Innovator in Enzyme Therapy
Introduction
Michel Couder is a notable inventor based in Sucy en Brie, France. He has made significant contributions to the field of enzyme therapy, particularly in the context of cancer treatment. With a total of 2 patents, Couder's work focuses on innovative approaches to targeting proliferative cells.
Latest Patents
Couder's latest patents include groundbreaking inventions related to enzyme combinations for destroying proliferative cells. These patents disclose a combination of enzymes that enhance the toxicity of nucleoside analogues to proliferating cells. Specifically, the invention involves an enzyme that phosphorylates a non-toxic nucleoside analogue to generate a monophosphate analogue, followed by further phosphorylation to produce a toxic triphosphate analogue. Additionally, vectors enabling the intracellular expression and transfer of these enzyme combinations are disclosed, highlighting their therapeutic potential in anti-cancer gene therapy.
Another significant patent involves variants of thymidine kinase, which are characterized by mutations in the ATP binding site and other regions. This invention relates to the use of these variants in gene therapy, showcasing Couder's commitment to advancing medical science through innovative solutions.
Career Highlights
Michel Couder has had a distinguished career, working with Aventis Pharma S.A., where he has been able to apply his expertise in enzyme therapy. His work has contributed to the development of novel therapeutic strategies aimed at combating cancer and improving patient outcomes.
Collaborations
Throughout his career, Couder has collaborated with esteemed colleagues such as Francis Blanche and Béatrice Cameron. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Michel Couder's contributions to enzyme therapy and cancer treatment exemplify the impact of innovative thinking in the medical field. His patents reflect a dedication to advancing therapeutic techniques that can potentially save lives.