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For the Inventor, By the Inventor

Montgeron, France

Michel Barreau

USPTO Granted Patents = 22

Average Co-Inventor Count = 5.5

ph-index = 5

Forward Citations = 94(Granted Patents)


Company Filing History:

goldMedal9 out of 247 
 
Rhone-poulenc Rorer S.a.
 patents
silverMedal7 out of 192 
 
Rhone-poulenc Sante
 patents
bronzeMedal5 out of 19 
 
Laboratoire Roger Bellon
 patents
4. 1 out of 1 
 
Rhone-pouelnc Rorer S.a.
 patent

Years Active: 1988-2000

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22 patents (USPTO):
1. 6057454 - 1-oxo-1H-inden-2-yl-1H-imidazole-2-carboxylic acid intermediates (2000-05-02),
2. 5922716 - 5H-indeno�1,2-b!pyrazine-2,3-dione derivatives, their preparation and (1999-07-13),
3. 5902803 - 5H,10H-imidazo�1,2-a!indeno�1,2-e!pyrazin-4-one derivatives, preparation (1999-05-11),
4. 5807859 - Imidazo (1,2-A)-Indeno (1,2-E) pyrazin-4-one derivatives and (1998-09-15),
5. 5789406 - Indeno�1,2-E!pyrazine-4-ones, their preparation and the medicaments (1998-08-04),
6. 5777114 - Spiro�heterocycle-imidazo�1,2-a!indeno�1,2-e!pyrazine!-4'-ones, (1998-07-07),
7. 5726175 - Imidazo�1,2-A!indeno�1,2-E!pyrazine-2-carboxylic acid derivatives, (1998-03-10),
8. 5676831 - Isoindolinone derivative, preparation thereof and pharmaceutical (1997-10-14),
9. 5599936 - Isoindolinone derivative, preparation thereof and pharmaceutical (1997-02-04),
10. 5556861 - 1,8 benzonaphthyridine derivatives and antimicrobial compositions (1996-09-17),
11. 5494915 - Isoindolinone derivative, preparation thereof, and pharmaceutical (1996-02-27),
12. 5403852 - Oxazole derivatives, their preparation and pharmaceutical compositions (1995-04-04),
13. 5225207 - Complexes derived from platinum, their preparation and the (1993-07-06),
14. 5053509 - Benzo[1,8]naphthyridine derivatives, their preparation and compositions (1991-10-01),
15. 5025013 - Benzopyran derivatives, their preparation and pharmaceutical (1991-06-18),

Title: **Michel Barreau: A Prolific Innovator in Pharmacological Compounds**


Introduction

Michel Barreau, a noted inventor based in Montgeron, France, has made significant strides in the field of medicinal chemistry. With an impressive portfolio of 22 patents, Barreau is recognized for his innovative contributions to pharmacology, particularly in the development of compounds with therapeutic applications.


Latest Patents

One of Barreau's latest patents includes the synthesis of 1-oxo-1H-inden-2-yl-1H-imidazole-2-carboxylic acid intermediates. This patent describes a compound of formula (II), which features various functional groups such as hydrogen, carboxy, and different radicals. The compounds of this formula are particularly noteworthy as they can be utilized to prepare compounds of formula (I), which exhibit valuable pharmacological properties. These compounds act as antagonists of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor and also function as non-competitive antagonists of the N-methyl-D-aspartate (NMDA) receptor, specifically serving as ligands for NMDA receptor glycine modulator sites.


Career Highlights

Throughout his career, Michel Barreau has collaborated with major pharmaceutical companies, such as Rhône-Poulenc Rorer S.A. and Rhône-Poulenc Santé. His focus on creating innovative medicinal compounds has led to numerous breakthroughs in pharmacology and therapeutic methodologies.


Collaborations

Barreau has had the privilege of working alongside esteemed colleagues like Jean-Claude Aloup and Dominique Damour. These collaborations have enriched his research and contributed to the successful development of various patented innovations.


Conclusion

Michel Barreau’s contributions to the field of pharmacology underscore the importance of innovation in developing new therapeutic agents. With a track record of 22 patents, his work continues to influence medical science and offers promise for future advancements in treatment options.

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