Michal Lotem

Michal Lotem is a prominent inventor based in Reut, Israel, known for his significant contributions to the field of cancer immunotherapy. With a total of five patents to his name, Lotem has focused on developing innovative therapeutic modalities aimed at improving cancer treatment outcomes.

Latest Patents

Lotem's latest patents include groundbreaking work on the modulation of SLAMF6 splice variants for cancer therapy. This invention relates to cancer immunotherapy, particularly enhancing therapeutic modalities that involve specifically modulating the expression and/or activity of SLAMF6 splice variants. The embodiments of this invention provide compositions and methods for cancer therapy, including adoptive T cell transfer therapies, cell vaccines, and polypeptide-based medicaments. Additionally, Lotem has developed methods for cancer therapy using isolated NTB-A ectodomain polypeptides. This invention is directed towards improved T cell modulation both ex vivo and in vivo, aimed at treating cancer and other pathologies.

Career Highlights

Throughout his career, Michal Lotem has worked with notable organizations such as Hadasit Medical Research Services and Development Ltd. and Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. His work has significantly advanced the field of immunotherapy, particularly in the context of cancer treatment.

Collaborations

Lotem has collaborated with esteemed colleagues, including Arthur Machlenkin and Shoshana Frankenburg, contributing to the development of innovative therapeutic strategies.

Conclusion

In summary, Michal Lotem is a distinguished inventor whose work in cancer immunotherapy has the potential to transform treatment approaches for patients. His innovative patents and collaborations highlight his commitment to advancing medical science and improving patient outcomes.

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