Location History:
- Oro Valley, AZ (US) (1995 - 2000)
- Tucson, AZ (US) (1997 - 2004)
Company Filing History:
9 out of 10 
1 out of 207 
2 out of 832,912 Years Active: 1995-2004
Title: Innovations and Contributions of Michal Lebl
Introduction
Michal Lebl is a prominent inventor based in Oro Valley, AZ (US), known for his significant contributions to the field of pharmaceuticals and biotechnology. With a total of 12 patents to his name, he has made remarkable advancements in the development of compounds that target specific biological activities.
Latest Patents
One of his latest patents focuses on Factor Xa inhibitors. This invention provides compounds that specifically inhibit factor Xa activity, characterized by the structure A —A —(A ) —B. These compounds exhibit a specific inhibition of factor Xa activity with a K ≤100 µM, preferably ≤2 nM, while not substantially inhibiting the activity of other proteases involved in the coagulation cascade. The invention also outlines methods for specifically inhibiting factor Xa activity and detecting factor Xa levels or activity. Another notable patent involves a method for producing combinatorial libraries with predetermined species of test compounds on solid phase supports. This technique ensures that each solid phase support contains only a single species of test compound, allowing for precise preparation without random division.
Career Highlights
Throughout his career, Michal Lebl has worked with various companies, including Selectide Corporation. His innovative approaches and dedication to research have positioned him as a key figure in his field.
Collaborations
He has collaborated with notable individuals such as Nikolai Sepetov and Kit S Lam, contributing to the advancement of scientific knowledge and innovation.
Conclusion
Michal Lebl's work exemplifies the spirit of innovation in the pharmaceutical industry. His patents and collaborations reflect a commitment to developing effective solutions for complex biological challenges.