Michael Thomas Brandl

Title: Michael Thomas Brandl: Innovator in Pharmaceutical Chemistry

Introduction

Michael Thomas Brandl is a notable inventor based in Redwood City, CA (US). He has made significant contributions to the field of pharmaceutical chemistry, holding a total of 3 patents. His work focuses on the development of novel crystalline forms and pharmaceutical compositions that have potential therapeutic applications.

Latest Patents

One of his latest patents involves the crystalline forms of N-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-N'-methoxyurea. This disclosure relates to the methods of making these crystalline forms, as well as pharmaceutical compositions and kits that include them. Another significant patent pertains to a method of forming granules of (2R,3S,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2-azido-3,4-bis-iso-butyryloxy-tetrahydro-furan-2-ylmethyl isobutyrate; hydrochloride salt. This invention describes a process that involves mixing the compound with a granulating liquid and a polyethylene glycol/polypropylene glycol block copolymer to create wet granules.

Career Highlights

Throughout his career, Michael has worked with various companies, including Roche Palo Alto LLC. His expertise in pharmaceutical chemistry has allowed him to contribute to innovative solutions in drug formulation and delivery.

Collaborations

Michael has collaborated with notable professionals in his field, including Kondamraj Birudaraj and Dimitrios Stefanidis. These collaborations have further enhanced his research and development efforts.

Conclusion

Michael Thomas Brandl is a distinguished inventor whose work in pharmaceutical chemistry has led to valuable innovations. His patents reflect a commitment to advancing drug formulation techniques and improving therapeutic outcomes.