Company Filing History:
Years Active: 2018-2025
Title: Innovations in Cardiac Function by Inventor Michael Regnier
Introduction
Michael Regnier is an accomplished inventor based in Bellevue, WA (US). He has made significant contributions to the field of cardiac health through his innovative research and patents. With a total of 2 patents, Regnier is dedicated to improving cardiac function and addressing serious heart conditions.
Latest Patents
Regnier's latest patents include groundbreaking work on engineering the RRM2 subunit of ribonucleotide reductase to resist degradation. This patent provides isolated nucleic acids that encode a stable form of Rrm2, which can be used to increase intracellular Rrm2 protein levels and cytosolic 2-deoxy-ATP (dATP) levels. The methods outlined in this patent aim to treat cardiac diseases or disorders, such as myocardial infarction or myocardial ischemia, by administering these isolated nucleic acids or the polypeptides they encode to patients in need.
Another notable patent focuses on cell and gene-based methods to improve cardiac function. This patent describes compositions and methods for enhancing myocardial contractility and relaxation in mammals. It involves grafting cardiomyocytes transfected with expression vectors that comprise ribonucleotide reductase subunit R1 and R2-encoding nucleic acid sequences to mammalian myocardium. The patent also discusses delivering dATP to the myocardium through grafting donor cells that overexpress R1 and R2, thereby producing dATP in situ.
Career Highlights
Michael Regnier is affiliated with the University of Washington, where he continues to advance his research in cardiac health. His work has garnered attention for its potential to revolutionize treatment options for heart diseases.
Collaborations
Regnier collaborates with esteemed colleagues, including Charles E. Murry and Michael Laflamme, to further enhance the impact of his research in the field of cardiac function.
Conclusion
Michael Regnier's innovative patents and research efforts are paving the way for new treatments in cardiac health. His dedication to improving heart function through scientific advancements is commendable and holds promise for future medical breakthroughs.