Michael Niehues

Title: Michael Niehues: Innovator in Pharmaceutical Chemistry

Introduction

Michael Niehues is a prominent inventor based in Berlin, Germany. He has made significant contributions to the field of pharmaceutical chemistry, particularly through his innovative work on triazolone compounds. With a total of five patents to his name, Niehues has established himself as a key figure in the development of new therapeutic agents.

Latest Patents

Among his latest patents, Niehues has developed compounds such as 4,5-annulated 1,2,4-triazolones. This invention provides triazolone compounds of general formula (I), where R, R, R, R, and R are defined within the patent. The methods of preparing these compounds, along with intermediate compounds useful for their synthesis, are also detailed. These compounds are aimed at manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, particularly hyperproliferative disorders. Another notable patent is for 2,4,5-trisubstituted 1,2,4-triazolones, which serve as inhibitors of DHODH. Similar to his previous work, this invention outlines the preparation methods and potential applications in pharmaceutical compositions.

Career Highlights

Michael Niehues has worked with esteemed institutions such as the Broad Institute, Inc. and Harvard College. His experience in these prestigious organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Some of his notable coworkers include Stefan Nikolaus Gradl and Duy Nguyen. Their collaborative efforts have further advanced the research and development of innovative pharmaceutical solutions.

Conclusion

Michael Niehues is a distinguished inventor whose work in pharmaceutical chemistry has led to the development of important therapeutic compounds. His contributions continue to impact the field and offer potential solutions for various medical conditions.