The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2023
Filed:
Jan. 28, 2021
Bayer Aktiengesellschaft, Leverkusen, DE;
Bayer Pharma Aktiengesellschaft, Berlin, DE;
The Broad Institute, Inc., Cambridge, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Stefan Nikolaus Gradl, Berlin, DE;
Duy Nguyen, Berlin, DE;
Knut Eis, Berlin, DE;
Judith Günther, Berlin, DE;
Timo Stellfeld, Berlin, DE;
Andreas Janzer, Berlin, DE;
Sven Christian, Berlin, DE;
Thomas Mueller, Langenfeld, DE;
Sherif El Sheikh, Mülheim/Ruhr, DE;
Han Jie Zhou, Foster City, CA (US);
Changjia Zhao, Beijing, CN;
David B. Sykes, Cambridge, MA (US);
Steven James Ferrara, Cambridge, MA (US);
Kery Liu, Beijing, CN;
Simon Anthony Herbert, Berlin, DE;
Claudia Merz, Berlin, DE;
Michael Niehues, Berlin, DE;
Carl Friedrich Nising, Berlin, DE;
Martina Schäfer, Berlin, DE;
Katja Zimmermann, Düsseldorf, DE;
Jörg Knäblein, Berlin, DE;
Kai Thede, Berlin, DE;
Thomas Faupel, Berlin, DE;
BAYER AKTIENGESELLSCHAFT, Leverkusen, DE;
BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;
THE BROAD INSTITUTE, INC., Cambridge, MA (US);
PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US);
THE GENERAL HOSPITAL CORPORATION, Boston, MA (US);
Abstract
The present invention provides triazolone compounds of general formula (I): in which R, R, R, Rand Rare as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.