Company Filing History:
2 out of 2,886 
1 out of 83 
Years Active: 1982-2008
Title: Michael N Margolies: Innovator in Monoclonal Antibody Development
Introduction
Michael N Margolies is a notable inventor based in Weston, MA (US). He has made significant contributions to the field of monoclonal antibodies, holding a total of 3 patents. His work focuses on developing antibodies with specific binding capabilities, which have important diagnostic and therapeutic applications.
Latest Patents
One of his latest patents is for Ouabain-specific monoclonal antibodies. This invention relates to a monoclonal antibody or antigen binding fragment that has binding specificity for ouabain, without cross-reacting with digoxin. The anti-ouabain monoclonal antibody can bind ouabain with an affinity of at least about 10M. The invention also encompasses diagnostic and therapeutic uses of these monoclonal antibodies. Another significant patent is for monoclonal antidigoxin antibodies. This invention discloses a hybridoma culture and high-affinity monoclonal antidigoxin antibodies produced by somatic cell fusion. These antibodies are useful for both therapeutic and diagnostic purposes, as well as in model systems for studying structure-function relationships in antigen-antibody specific reactions.
Career Highlights
Throughout his career, Michael N Margolies has worked with prominent institutions, including The General Hospital Corporation and Massachusetts General Hospital Corporation. His work has contributed to advancements in medical diagnostics and therapeutics, particularly in the area of antibody development.
Collaborations
Michael has collaborated with esteemed colleagues such as Edgar Haber and Paul H Ehrlich. These collaborations have further enhanced the impact of his research and innovations in the field.
Conclusion
Michael N Margolies is a distinguished inventor whose work in monoclonal antibodies has paved the way for significant advancements in medical science. His contributions continue to influence the development of diagnostic and therapeutic tools in healthcare.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.