The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2008
Filed:
Oct. 05, 1999
Behnaz Parhami-seren, Brookline, MA (US);
Michael N. Margolies, Weston, MA (US);
Garner T. Haupert, Jr., Littleton, MA (US);
Behnaz Parhami-Seren, Brookline, MA (US);
Michael N. Margolies, Weston, MA (US);
Garner T. Haupert, Jr., Littleton, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
The invention relates to a monoclonal antibody or antigen binding fragment thereof having binding specificity for ouabain, wherein the antibody or antigen binding fragment does not crossreact with digoxin. Preferably the anti-ouabain monoclonal antibody can bind ouabain with an affinity of at least about 10M, preferably 10M, and more preferably 10M. The invention also relates to diagnostic and therapeutic uses of the monoclonal antibodies described herein.