Company Filing History:
Years Active: 1993-2011
Title: Innovations and Contributions of Michael N Gould
Introduction
Michael N Gould is a prominent inventor based in Madison, WI (US). He has made significant contributions to the field of genetics and cancer research, holding a total of 11 patents. His work focuses on understanding genetic mutations and their implications for cancer susceptibility.
Latest Patents
One of his latest patents involves a mutation in the rat adenomatous polyposis coli gene within the human mutation hotspot region. This patent describes a rat with a disrupted Apc (adenomatous polyposis coli) gene, which includes an A to T transversion that changes a lysine to a stop codon at codon 1137. The patent also provides methods for generating the knockout rat and discusses the offspring or progeny of that rat. Additionally, it outlines methods for using these rats, including screening for carcinogens or promoters of carcinogenesis, as well as preventive and inhibitory agents of carcinogenesis. Another significant patent focuses on a method of analyzing breast cancer susceptibility and resistance. This method involves obtaining a DNA sample from a patient, genotyping the sample for the presence of specific single nucleotide polymorphisms, and correlating the allele identity with risk assessment data.
Career Highlights
Michael N Gould is associated with the Wisconsin Alumni Research Foundation, where he continues to advance his research and innovations. His work has been instrumental in developing new methodologies for cancer research and genetic analysis.
Collaborations
He has collaborated with notable colleagues, including Pamela L Crowell and Charles E Elson, contributing to a rich environment of innovation and discovery.
Conclusion
Michael N Gould's contributions to genetic research and cancer susceptibility analysis highlight his role as a leading inventor in his field. His patents reflect a commitment to advancing scientific knowledge and improving health outcomes.