Michael Meldgaard

Title: Michael Meldgaard: Innovator in Quencher Compositions

Introduction

Michael Meldgaard is a notable inventor based in Hillerod, Denmark. He has made significant contributions to the field of biochemistry, particularly in the development of novel quencher compositions. His work focuses on enhancing the functionality of biomolecules through innovative labeling techniques.

Latest Patents

Meldgaard holds a patent for "Quencher compositions comprising anthraquinone moieties." This invention provides a unique quencher composition that includes anthraquinone quencher moieties. These moieties are particularly useful as quencher labels when attached to various biomolecules, such as natural or modified polynucleotides, oligonucleotides, nucleosides, nucleotides, carbohydrates, and peptides. The patent outlines methods for labeling polynucleotides at the 3' terminus with fluorescence quencher solid support compositions, as well as labeling them internally or at the 5' terminus. The detectable probes developed from this invention can take formats like molecular beacons, scorpion probes, sunrise probes, conformationally assisted probes, and TaqMan probes.

Career Highlights

Meldgaard's career is marked by his innovative approach to biochemistry and molecular biology. His work has led to advancements in the field, particularly in the area of fluorescence labeling. He is currently associated with Exiqon A/S, a company known for its focus on molecular diagnostics and research tools.

Collaborations

Throughout his career, Meldgaard has collaborated with several professionals in the field, including Christian Lomholt and Henrik M Pfundheller. These collaborations have contributed to the development and refinement of his innovative technologies.

Conclusion

Michael Meldgaard is a prominent figure in the realm of biochemistry, with a focus on quencher compositions that enhance biomolecular labeling. His contributions continue to influence research and development in molecular diagnostics.