The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2009

Filed:

Nov. 19, 2004
Applicants:

Christian Lomholt, Frederiksberg C, DK;

Henrik M. Pfundheller, Horsholm, DK;

Michael Meldgaard, Hillerod, DK;

Inventors:

Christian Lomholt, Frederiksberg C, DK;

Henrik M. Pfundheller, Horsholm, DK;

Michael Meldgaard, Hillerod, DK;

Assignee:

Exiqon A/S, Vedbaek, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 19/04 (2006.01); C12Q 1/68 (2006.01); C07D 265/34 (2006.01); C07C 46/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel quencher composition comprising anthraquinone quencher moieties. The anthraquinone quencher moieties are useful as quencher labels when attached to biomolecules such as natural or modified polynucleotides, oligonucleotides, nucleosides, nucleotides, carbohydrates and peptides. For example, polynucleotides can be labeled at the 3' terminus with fluorescence quencher solid support compositions, and polynucleotides can be labeled at internally or at the 5′ terminus. The detectable probes may have a format like molecular beacons, scorpion probes, sunrise probes, conformationally assisted probes and TaqMan probes.


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