Location History:
- Frederiksberg, DK (2003 - 2004)
- Horsholm, DK (2009)
Company Filing History:
Years Active: 2003-2009
Title: Innovations of Henrik M Pfundheller
Introduction
Henrik M Pfundheller is a notable inventor based in Frederiksberg, Denmark. He has made significant contributions to the field of biochemistry and molecular biology through his innovative patents. With a total of three patents to his name, Pfundheller has focused on developing novel compositions and synthesis methods that enhance the functionality of biomolecules.
Latest Patents
One of his latest patents is titled "Quencher compositions comprising anthraquinone moieties." This invention provides a novel quencher composition that includes anthraquinone quencher moieties. These moieties are particularly useful as quencher labels when attached to biomolecules such as natural or modified polynucleotides, oligonucleotides, nucleosides, nucleotides, carbohydrates, and peptides. For instance, polynucleotides can be labeled at the 3' terminus with fluorescence quencher solid support compositions, and they can also be labeled internally or at the 5' terminus. The detectable probes may take various formats, including molecular beacons, scorpion probes, sunrise probes, conformationally assisted probes, and TaqMan probes.
Another significant patent is related to the "Synthesis of [2.2.1]bicyclo nucleosides." This synthesis method is shorter and yields higher overall results. It proceeds via a key intermediate of a general formula, allowing for the coupling with silylated nucleobases. The process demonstrates a short route to Locked Nucleic Acid (LNA) derivatives of adenosine, cytosine, uridine, thymidine, and guanidine. The use of the 5'-sulfonated ring-closed intermediate also facilitates the synthesis of 5'-amino- and thio-LNAs.
Career Highlights
Henrik M Pfundheller is currently associated with Exiqon A/S, a company known for its advancements in molecular biology tools. His work at Exiqon has allowed him to focus on innovative solutions that address complex challenges in the field.
Collaborations
Throughout his career, Pfundheller has collaborated with notable colleagues, including Alexei Kochkine and Jef Fensholdt. These collaborations have contributed to the development of his patents and the advancement of research in molecular biology.
Conclusion
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.