Michael Maurer

Title: Michael Maurer: Innovator in Protein Production

Introduction

Michael Maurer is a prominent inventor based in Vienna, Austria. He has made significant contributions to the field of protein production, holding a total of 5 patents. His innovative approaches have advanced the methodologies used in recombinant eukaryotic cell lines.

Latest Patents

Among his latest patents, Maurer has developed methods for producing promoter variants for protein production. This involves culturing a recombinant eukaryotic cell line that includes an expression construct with a regulatable promoter and a nucleic acid molecule encoding a protein of interest (POI). The process includes several steps: first, cultivating the cell line with a basal carbon source that represses the promoter; second, using a limited amount of a supplemental carbon source to de-repress the promoter, inducing production of the POI at a transcription rate of at least 15% compared to the native pGAP promoter; and finally, producing and recovering the POI. Additionally, he has patented methods for producing promoter variants, which follow a similar process.

Career Highlights

Michael Maurer has worked with notable organizations such as Lonza Inc. and Universität Für Bodenkultur Wien. His experience in these institutions has allowed him to refine his expertise in protein production and related technologies.

Collaborations

Throughout his career, Maurer has collaborated with esteemed colleagues, including Diethard Mattanovich and Brigitte Gasser. These partnerships have further enriched his research and development efforts.

Conclusion

Michael Maurer stands out as an influential inventor in the realm of protein production, with a solid portfolio of patents that reflect his innovative spirit and dedication to advancing biotechnology.