Location History:
- Roosevelt Island, NY (US) (1997)
- New York, NY (US) (1997 - 2000)
Company Filing History:
2 out of 26 
1 out of 1,327 
1 out of 1 Years Active: 1997-2000
Title: Innovating RNA Treatment: The Contributions of Inventor Michael Ma
Introduction
Michael Ma, an innovative inventor based in New York, NY, has made significant strides in the field of molecular biology and RNA technology. With a total of five patents to his name, Ma's work is at the forefront of developing solutions for critical health challenges, particularly in the treatment of viral infections.
Latest Patents
Among his notable inventions, Ma has developed "Stabilized External Guide Sequences," which refers to modified external guide sequence (EGS) molecules specifically designed to mediate the cleavage of target RNAs. These modified molecules enhance their nuclease resistance while maintaining RNAse P activity, making them suitable for treating hepatitis B viral infections.
Additionally, he holds a patent for "Polynucleotide Phosphorodithioate Compounds." This invention includes nucleoside thiophosphoroamidites and polynucleotide phosphorodithioate compounds, facilitating the synthesis of new mononucleotides and polynucleotides with phosphorothioate and phosphorodithioate internucleotide linkages. These advancements showcase Ma's commitment to pushing the boundaries of RNA technology.
Career Highlights
Michael Ma has held influential positions at several prestigious institutions, including Competitive Technologies, Inc. and Yale University. His experience in these organizations has equipped him with the skills and knowledge necessary to drive innovation in his field.
Collaborations
Throughout his career, Ma has collaborated with esteemed scientists such as Marvin H. Caruthers and Wolfgang K-d Brill. These partnerships have fostered significant advancements in RNA research and have contributed to the successful development of his patented technologies.
Conclusion
With his innovative patents and collaborative efforts, Michael Ma is a prominent figure in the realm of RNA technology. His work not only presents groundbreaking solutions for hepatitis B treatment but also highlights the importance of continued research and innovation in the field of molecular biology.