Michael Lutterman

Title: Innovations by Michael Lutterman

Introduction

Michael Lutterman is an accomplished inventor based in New Brighton, MN (US). He has made significant contributions to the field of medical diagnostics, particularly in the detection of vitamin D and its implications for renal health. With a total of four patents to his name, Lutterman continues to push the boundaries of innovation in his field.

Latest Patents

Lutterman's latest patents include methods for detecting 1,25-dihydroxyvitamin D and related antibodies. This patent discloses an assay method for selectively detecting 1,25-dihydroxyvitamin D in biological fluid samples. The method involves adjusting the pH of the test sample to between 6 and 9 and adding a receptor protein comprising the Ligand Binding Domain of Vitamin D Receptor (VDR-LBD). This results in the formation of a VDR-LBD/1,25-dihydroxyvitamin D complex, which can be detected using a capture moiety that specifically binds to the complex. The assay is preferably a sandwich immunoassay.

Another significant patent relates to the use of 1,25-dihydroxyvitamin D values in ratio with parathyroid hormone (PTH) as a prognostic biomarker. This invention provides a method for predicting or stratifying the risk of worsening renal function in patients at risk of renal injury. By measuring levels of 1,25-dihydroxyvitamin D in conjunction with PTH levels, a ratio can be established that indicates the risk of worsening renal function.

Career Highlights

Lutterman is currently employed at Diasorin S.p.a., where he applies his expertise in medical diagnostics. His work has been instrumental in developing innovative solutions that enhance patient care and improve diagnostic accuracy.

Collaborations

Some of Lutterman's notable coworkers include Joshua Soldo and Gregory Olson. Their collaborative efforts contribute to the advancement of research and development in the field of medical diagnostics.

Conclusion

Michael Lutterman is a notable inventor whose work in the detection of vitamin D and its implications for renal health has made a significant impact in the medical field. His innovative patents and contributions continue to pave the way for advancements in diagnostic methods.