The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Jul. 17, 2017
Diasorin S.p.a., Saluggia, IT;
Francesco Colotta, Segrate, IT;
Fabrizio Bonelli, Casale Monferrato, IT;
Frank Blocki, Hayfield, MN (US);
Claudia Zierold, St. Paul, MN (US);
Joshua Soldo, Prior Lake, MN (US);
Gregory Olson, Lakeland, MN (US);
Michael Lutterman, New Brighton, MN (US);
John Wall, Woodbury, MN (US);
Michael New, Bloomington, MN (US);
Hector Floyd Deluca, Deerfield, WI (US);
DiaSorin S.p.A., Saluggia, IT;
Abstract
The present invention relates to the use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker. More particularly, the present invention relates to a method for predicting or stratifying the risk of worsening renal function (WRF) in a patient at risk of renal injury or affected by renal injury. Levels of 1,25-dihydroxyvitamin D (1,25(OH)D) are measured in a biological sample and taken together with parathyroid hormone (PTH) levels to provide a ratio indicative of the risk of worsening renal function.