Location History:
- Casale Monferrato, IT (2019 - 2021)
- Alessandria, IT (2019 - 2022)
Company Filing History:
Years Active: 2019-2022
Title: Innovations of Fabrizio Bonelli in Vitamin D Detection
Introduction
Fabrizio Bonelli is a notable inventor based in Alessandria, Italy. He has made significant contributions to the field of medical diagnostics, particularly in the detection of vitamin D and its related biomarkers. With a total of four patents to his name, Bonelli's work has the potential to impact patient care and treatment strategies.
Latest Patents
One of Bonelli's latest patents is focused on methods for detecting 1,25-dihydroxyvitamin D and related antibodies. This patent discloses an assay method for selectively detecting 1,25-dihydroxyvitamin D in biological fluid samples. The method involves adjusting the pH of the test sample to between 6 and 9 and adding a receptor protein that comprises the Ligand Binding Domain of the Vitamin D Receptor (VDR-LBD). This process leads to the formation of a VDR-LBD/1,25-dihydroxyvitamin D complex, which can be detected using a capture moiety that specifically binds to the complex. The assay is preferably a sandwich immunoassay.
Another significant patent relates to the use of 1,25-dihydroxyvitamin D values in ratio with parathyroid hormone (PTH) as a prognostic biomarker. This invention provides a method for predicting or stratifying the risk of worsening renal function in patients at risk of renal injury. By measuring levels of 1,25-dihydroxyvitamin D in conjunction with PTH levels, healthcare providers can obtain a ratio that indicates the risk of worsening renal function.
Career Highlights
Fabrizio Bonelli is currently employed at Diasorin S.p.a., a company known for its innovative diagnostic solutions. His work at Diasorin has allowed him to focus on developing advanced diagnostic methods that can improve patient outcomes.
Collaborations
Bonelli has collaborated with notable colleagues such as Joshua Soldo and Gregory Olson. These collaborations have likely contributed to the advancement of his research and the successful development of his patents.
Conclusion
Fabrizio Bonelli's contributions to the field of vitamin D detection and renal function assessment highlight the importance of innovation in medical diagnostics. His patents reflect a commitment to improving healthcare through advanced technology and research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.