John Wall

Title: The Innovative Contributions of John Wall

Introduction

John Wall is a notable inventor based in Woodbury, MN (US), recognized for his significant contributions to the field of medical diagnostics. With a total of 8 patents to his name, Wall has focused on advancing methods for detecting vital biomarkers that can aid in the assessment of renal function.

Latest Patents

One of Wall's latest patents is titled "Methods for detecting 1,25-dihydroxyvitamin D and related antibodies." This invention discloses an assay method for selectively detecting 1,25-dihydroxyvitamin D in biological fluid samples. The method involves adjusting the pH of the test sample to a range of 6-9 and adding a receptor protein that comprises the Ligand Binding Domain of the Vitamin D Receptor (VDR-LBD). This process results in the formation of a VDR-LBD/1,25-dihydroxyvitamin D complex, which can be detected using a capture moiety that specifically binds to the complex. The assay is preferably a sandwich immunoassay.

Another significant patent by Wall relates to the "Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker." This invention focuses on predicting or stratifying the risk of worsening renal function in patients at risk of renal injury. By measuring levels of 1,25-dihydroxyvitamin D in conjunction with parathyroid hormone (PTH) levels, the method provides a ratio that indicates the risk of worsening renal function.

Career Highlights

Throughout his career, John Wall has worked with prominent companies in the medical diagnostics field, including Surmodics, Inc. and Diasorin S.p.a. His work has significantly impacted the development of diagnostic tools that enhance patient care and treatment outcomes.

Collaborations

Wall has collaborated with talented individuals such as Joshua Soldo and Gregory Olson, contributing to the advancement of innovative medical technologies.

Conclusion

John Wall's contributions to the field of medical diagnostics through his patents and collaborations highlight his commitment to improving healthcare solutions. His innovative methods for detecting biomarkers are paving the way for better patient outcomes in renal health.