Company Filing History:
Years Active: 2023
Title: The Innovative Contributions of Michael L. Cronce
Introduction
Michael L. Cronce is an accomplished inventor based in Roxbury, Massachusetts. He has made significant strides in the field of biomedical engineering, particularly in the development of microfluidic devices that mimic human gut environments. His work is crucial for advancing our understanding of the human microbiome and its interactions with intestinal cells.
Latest Patents
Michael L. Cronce holds a patent for a groundbreaking invention titled "Complex human gut microbiome cultured in an anaerobic human gut-on-a-chip." This microfluidic device is designed to sustain a complex microbial community in direct and indirect contact with living human intestinal cells in vitro. The device features a first microchannel containing cultured cells of human intestinal epithelium and microbiota, which operates at a specific level of oxygen. Additionally, it includes a second microchannel with cultured cells of vascular endothelium, also at a designated oxygen level. A membrane at the interface between the two microchannels is composed of an oxygen-permeable material, allowing for the formation of a physiologically relevant oxygen gradient.
Career Highlights
Michael L. Cronce is affiliated with Harvard College, where he continues to contribute to innovative research in the field of microbiome studies. His work has implications for understanding gut health and developing new therapeutic strategies.
Collaborations
Michael collaborates with notable colleagues, including Richard Novak and Sasan Jalili-Firoozinezhad. Their combined expertise enhances the research and development of advanced biomedical technologies.
Conclusion
Michael L. Cronce's contributions to the field of biomedical engineering, particularly through his innovative patent, highlight the importance of research in understanding human health. His work at Harvard College and collaborations with esteemed colleagues further underscore his commitment to advancing scientific knowledge.