Company Filing History:
Years Active: 2017-2025
Title: Innovations of Michael E Kopach
Introduction
Michael E Kopach is a notable inventor based in Greenwood, IN (US). He has made significant contributions to the field of peptide synthesis, holding a total of 5 patents. His work focuses on developing advanced methods and devices for manufacturing peptides, which are essential in various pharmaceutical applications.
Latest Patents
One of his latest patents is a "Three resin reactors in series peptide synthesizer." This Solid Phase Peptide Synthesis (SPPS) device and method is designed for the efficient manufacturing of peptides. The system comprises at least two reactors, each containing a quantity of SPPS resin, positioned in series. A de-protecting agent is added to the first reactor and then transferred to the subsequent reactors, effectively de-protecting the protected N-group. The process involves adding wash solvent and amino acid activated ester solutions in a series manner, which optimizes the coupling of amino acids to the de-protected N-group. This innovative approach reduces the overall solvent required and incorporates online LCMS to monitor the reactions occurring within the solid phase resin particles.
Another significant patent involves "Processes and intermediates for preparing tirzepatide." This invention provides new intermediates and processes that are useful in the manufacture of tirzepatide, or a pharmaceutically acceptable salt thereof.
Career Highlights
Throughout his career, Michael E Kopach has worked with prominent companies in the pharmaceutical industry, including Eli Lilly and Company and Vanda Pharmaceuticals Inc. His expertise in peptide synthesis has made him a valuable asset in these organizations.
Collaborations
Michael has collaborated with notable professionals in his field, including Michael Edward Kobierski and Pingyun Chen. Their combined efforts have contributed to advancements in peptide synthesis technologies.
Conclusion
Michael E Kopach's innovative work in peptide synthesis and his contributions to the pharmaceutical industry highlight his importance as an inventor. His patents reflect a commitment to improving manufacturing processes and advancing scientific knowledge in the field.