Location History:
- Urbana, IL (US) (2009)
- Honolulu, HI (US) (2015 - 2020)
Company Filing History:
Years Active: 2009-2020
Title: Michael D. Okura: Innovator in Nucleic Acid Hybridization
Introduction
Michael D. Okura is a prominent inventor based in Honolulu, HI (US). He has made significant contributions to the field of nucleic acid hybridization, holding a total of 5 patents. His work focuses on enhancing the specificity of nucleic acid analysis, which is crucial for various applications in genetics and molecular biology.
Latest Patents
One of Michael D. Okura's latest patents is titled "Systems, methods, and compositions for enhancing the specificity of nucleic acid hybridization." This invention can be utilized in capture/enrichment, gene expression profiling, and targeted sequencing. The systems and methods he developed enhance the specificity of nucleic acid hybridization and control the shapes of melting curves revealed by nucleic acid hybrid pairs. This optimization allows for improved nucleic acid analysis. The invention involves producing a positively charged surface or surface coating on microarray slides or similar surfaces, which significantly enhances melting curve analysis. This advancement enables the detection or differentiation of small changes in sequences between nucleic acid binding partners. The accuracy of melting curve analysis is sufficient to distinguish between perfectly matched dsDNA and dsDNA with a one base pair mismatch.
Career Highlights
Throughout his career, Michael D. Okura has worked with various companies, including Emergence Genomics, LLC. His innovative approaches have led to advancements in the field of molecular diagnostics and genetic research.
Collaborations
Michael has collaborated with notable individuals in his field, including Bruce J. Richardson and Billy B. McNeill. These collaborations have contributed to the development of his groundbreaking technologies.
Conclusion
Michael D. Okura is a distinguished inventor whose work in nucleic acid hybridization has paved the way for advancements in genetic analysis. His contributions continue to impact the scientific community and enhance our understanding of molecular biology.