Location History:
- Tulsa, OK (US) (1986)
- Menlo Park, CA (US) (2012 - 2022)
Company Filing History:
19 out of 459 
2 out of 832,680 Years Active: 1986-2025
Title: Innovations and Contributions of Michael D. Clay in Biocatalysis
Introduction
Michael D. Clay, based in Menlo Park, CA, is a notable inventor recognized for his significant contributions in the field of biocatalysis. With a remarkable portfolio of 20 patents, he has blended scientific research with innovation to advance synthetic methods in pharmaceuticals, especially concerning armodafinil.
Latest Patents
One of his latest patents, titled "Biocatalysts and methods for the synthesis of armodafinil," focuses on the development of non-naturally occurring polypeptides. The invention highlights polynucleotides that encode these innovative polypeptides, which play a crucial role in the biocatalytic conversion processes involved in producing armodafinil. The process includes two primary transformations: converting 2-(benzhydrylsulfinyl)acetamide into (-)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil) and transforming benzhydryl-thioacetic acid into (R)-2-(benzhydrylsulfinyl)acetic acid, a key intermediate in armodafinil synthesis, all achieved in enantiomeric excess.
Career Highlights
Throughout his career, Michael D. Clay has collaborated with prominent industry players, notably including Codexis, Inc. His innovative work in synthetic methodologies and biocatalysis has positioned him as a leader in the field, significantly contributing to pharmaceutical advancements.
Collaborations
In addition to his work at Codexis, Michael has worked alongside talented colleagues such as Steven James Collier and Shiwei Song. These collaborations have fostered a dynamic research environment, leading to groundbreaking innovations in biocatalytic processes.
Conclusion
Michael D. Clay's contributions to the field of biocatalysis and his array of patents demonstrate the profound impact of his work on modern pharmaceutical synthesis. Through his innovations, he continues to shape the landscape of biocatalytic methods, paving the way for future advancements in the industry.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.