Location History:
- Somerville, MA (US) (2011)
- Cambridge, MA (US) (2019)
Company Filing History:
1 out of 2,893 
1 out of 1,036 
Years Active: 2011-2019
Title: The Innovative Mind of Michael Costigan
Introduction
Michael Costigan is a notable inventor based in Cambridge, MA, United States. With two patents to his name, he has made significant contributions to the fields of medicine and biochemistry, particularly focusing on the mechanisms of pain treatment and inhibition methods.
Latest Patents
Costigan’s latest patents reflect his dedication to advancing medical science. The first patent, titled "Methods and assays relating to sepiapterin reductase inhibition," details innovative methods and assays for inhibiting sepiapterin reductase and measuring its inhibition through the level of sepiapterin. This invention includes treatment methods for subjects using BH4 and/or BH2, promising new avenues in therapeutic approaches.
The second patent, "Methods for treating pain," presents groundbreaking methods and compositions aimed at preventing, reducing, or treating various types of nerve-related pain. This includes neuropathic, inflammatory, and nociceptive pain. By administering compounds that reduce the expression or activity of BH4, this invention offers a fresh perspective on pain management, exploring the inhibition of critical enzymes involved in BH4 synthesis.
Career Highlights
Throughout his career, Michael Costigan has been associated with esteemed institutions such as the General Hospital Corporation and Children's Medical Center Corporation. His work in these organizations laid the foundation for his subsequent innovations, illustrating a strong commitment to improving patient outcomes through scientific research.
Collaborations
In his journey as an inventor, Costigan has collaborated with distinguished colleagues, including Clifford J. Woolf and Robert Griffin. Their collective expertise has played a vital role in advancing their shared interests in pain research and therapeutic developments, fostering an environment of innovation and discovery.
Conclusion
Michael Costigan stands out as an influential inventor in the scientific community. Through his innovative patents and collaborations with leading researchers, he continues to pave the way for new therapeutic strategies, ultimately striving to alleviate pain and enhance quality of life for many. His dedication and contributions to the field of biochemistry exemplify the spirit of innovation essential for transformative advancements in healthcare.