The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2019
Filed:
Oct. 29, 2015
Applicant:
Children's Medical Center Corporation, Boston, MA (US);
Inventors:
Clifford J. Woolf, Newton, MA (US);
Alexandra S. Latini, Brookline, MA (US);
Nick A. Andrews, Cambridge, MA (US);
Alban Latremoliere, Boston, MA (US);
Michael Costigan, Cambridge, MA (US);
Assignee:
CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4045 (2006.01); G01N 33/50 (2006.01); C12Q 1/26 (2006.01); A61K 31/519 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5038 (2013.01); A61K 31/4045 (2013.01); A61K 31/519 (2013.01); C12Q 1/26 (2013.01); G01N 33/487 (2013.01); G01N 33/5008 (2013.01); G01N 2560/00 (2013.01); G01N 2800/52 (2013.01);
Abstract
Described herein are methods and assays relating to the inhibition of sepiapterin reductase and measuring said inhibition by measuring the level of sepiapterin. In some embodiments, the methods can further relate to treating a subject with BH4 and/or BH2.