This inventor holds 1 USPTO granted patent. Top assignee: University of California. Active years: 2018.
Company Filing History:
Years Active: 2018
Title: Michael Bassik: Innovator in Genetic Interaction Mapping
Introduction
Michael Bassik is a prominent inventor based in San Francisco, CA. He has made significant contributions to the field of genetics, particularly in the area of genome-wide screening. His innovative work has the potential to advance our understanding of genetic interactions and their implications for therapy.
Latest Patents
Michael Bassik holds a patent titled "Methods for genome-wide screening and construction of genetic interaction maps." This invention provides methods for conducting screens using nucleic acid elements, such as interfering RNAs, to confidently identify hit genetic elements. The invention also includes constructing vectors that contain two or more nucleic acid elements to knock down all pairwise combinations of the identified hit genetic elements. Following the quantitation of the single and double-knockdown phenotypes, genetic interactions between all gene pairs can be calculated. This process allows for the clustering of genes based on the similarity of their interaction patterns, ultimately leading to the creation of a genetic interaction map. This map can be used to predict functional associations between genes and identify drug targets for therapies, including combination cancer therapy. Michael Bassik has 1 patent to his name.
Career Highlights
Michael Bassik is affiliated with the University of California, where he continues to engage in groundbreaking research. His work has garnered attention for its innovative approach to understanding genetic interactions and their applications in therapeutic contexts.
Collaborations
Some of his notable coworkers include Jonathan S. Weissman and Martin Kampmann. Their collaborative efforts contribute to the advancement of research in genetic interactions and therapeutic applications.
Conclusion
Michael Bassik's contributions to the field of genetics through his innovative patent and research at the University of California highlight his role as a key figure in advancing our understanding of genetic interactions. His work has the potential to significantly impact therapeutic strategies in the future.