Location History:
- Oxon, GB (2003 - 2009)
- Watlington, GB (2020)
Company Filing History:
Years Active: 2003-2020
Title: Michael Anthony William Eaton: Innovator in Gene Therapy
Introduction
Michael Anthony William Eaton is a notable inventor based in Oxon, GB. He has made significant contributions to the field of gene therapy, holding a total of 3 patents. His work focuses on developing innovative compounds and lipids that enhance the delivery of nucleic acids for therapeutic purposes.
Latest Patents
Eaton's latest patents include groundbreaking inventions such as endosomolytic agents for gene therapy. These agents consist of compounds of formula (I), where Ar is an aryl group that may be substituted with various groups R. A is a lipophilic, hydrophobic moiety, while R can be a phosphodiester, phosphotriester, thioether, or amide group. Additionally, X represents an unsubstituted or substituted C to C alkylene or alkenylene group, which may be interrupted by one or more linkages. These compounds are particularly useful for delivering nucleic acids in gene therapy. Another significant patent involves bipolar lipids that can form complexes with polyanions. These lipids feature a cationic head linked to a hydrophobic backbone and a hydrophilic tail, allowing them to self-assemble into stable complexes in aqueous solutions. They are especially valuable for delivering bioactive substances, such as nucleic acids, to cells both in vitro and in vivo.
Career Highlights
Throughout his career, Eaton has worked with prominent companies in the biotechnology sector, including Celltech R&D Limited and UCB Biopharma. His experience in these organizations has contributed to his expertise in developing innovative solutions for gene therapy.
Collaborations
Eaton has collaborated with notable professionals in his field, including Timothy John Norman and Terence Seward Baker. These collaborations have further enriched his research and development efforts.
Conclusion
Michael Anthony William Eaton is a distinguished inventor whose work in gene therapy has the potential to transform medical treatments. His innovative patents and collaborations highlight his commitment to advancing the field.