The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Sep. 27, 2017
Ucb Biopharma Srl, Brussels, BE;
Terence Seward Baker, Slough, GB;
Michael Anthony William Eaton, Watlington, GB;
Timothy John Norman, Slough, GB;
James Petrie Turner, Slough, GB;
UCB Biopharma SRL, Brussels, BE;
Abstract
Compounds of formula (I), wherein Ar is an aryl group optionally further substituted with one or more groups R; A is a lipophilic, hydrophobic moiety; Ris a phosphodiester, phosphotriester, thioether or amide group; X is an unsubstituted or substituted Cto Calkylene or alkenylene group, which is optionally interrupted by one or more —NR—, —O— or —S— linkages, Ris —YC(R)(R)COR; and pharmaceutically acceptable salts or solvates thereof are useful as endosomolytic agents particularly for the delivery of nucleic acids useful in gene therapy.