Michael A Thompson

Title: **Innovator Michael A. Thompson: Pioneering Advances in Molecular Imaging**

Introduction

Michael A. Thompson is an innovative inventor based in Orange, California. He holds two patents that showcase his commitment to advancing scientific understanding and imaging techniques.

Latest Patents

Among his notable patents is the invention titled "Three-dimensional single-molecule fluorescence imaging beyond the diffraction limit using a double-helix point spread function." This groundbreaking technology allows for the resolution of molecules beyond the optical diffraction limit in three dimensions. By utilizing a double-helix point spread function in conjunction with a microscope, it provides dual-lobed images of individual molecules. The rotation of these dual-lobed images enables precise estimation of a molecule’s axial position. Techniques such as centroid fit calculation or identifying midpoints between the lobes further enhance the determination of molecular location, both laterally and axially.

Career Highlights

Michael is affiliated with the University of Colorado, where he continues to contribute to the field of molecular imaging. His pioneering work has greatly improved techniques for visualizing molecular structures and interactions in a detailed manner.

Collaborations

Throughout his career, Michael has collaborated with esteemed colleagues, including Rafael Piestun and Sri Rama Prasanna Pavani. These partnerships have facilitated important innovations and advancements in their shared field of research.

Conclusion

Michael A. Thompson stands out as a significant inventor in the realm of scientific imaging. His patents not only reflect his expertise but also highlight the potential for future advancements in molecular visualization through innovative techniques. His work continues to inspire new directions in research and application.