Company Filing History:
Years Active: 1995-2001
Title: Michael A. Romanos: Innovator in Biotechnology
Introduction
Michael A. Romanos is a notable inventor based in Beckenham, GB, recognized for his contributions to the field of biotechnology. With three patents to his name, Romanos has significantly advanced the production and expression of critical antigens, contributing to developments in medical research and applications.
Latest Patents
Romanos' latest patents showcase his innovative approaches to genetic expression. One of his notable patents involves the transformation of Pichia yeast to express the Bordetella pertactin antigen. This patent details the production of Bordetella pertactin antigens through expression in methyltrophic yeast, involving expression vectors containing DNA that encodes the antigens and transformation methods for Pichia yeast.
Another significant patent focuses on the expression of the tetanus toxin fragment C in yeast. This technology utilizes a DNA coding sequence designed to increase the (G+C)-content in specific regions of the coding sequence. By enhancing the (G+C)-content from nucleotide 410 to the 3' end, this method allows for the production of complete mRNA transcripts, improving the overall efficiency of antigen production.
Career Highlights
Throughout his career, Michael Romanos has made impactful contributions to various organizations. Noteworthy companies he has worked at include Evans Medical Limited and Medeva Pharma Limited. His expertise in biotechnology has led to significant advancements in the field, particularly regarding vaccine development and production.
Collaborations
During his professional journey, Romanos has collaborated with other accomplished scientists, including Jeffrey J. Clare and Andrew J. Makoff. These collaborations have further enriched his research endeavors and have contributed to the development of innovative solutions in biotechnology.
Conclusion
Michael A. Romanos is a distinguished inventor in the field of biotechnology. With his groundbreaking patents and collaborative efforts, he has played a vital role in advancing the understanding and production of critical medical antigens. His work continues to inspire new innovations within the industry.