Company Filing History:
7 out of 1,309 
1 out of 2,620 
Years Active: 2011-2018
Title: Menelas N Pangalos: Innovator in Muscle and Bone Health
Introduction
Menelas N Pangalos is a notable inventor based in Pennington, NJ (US). He has made significant contributions to the field of medical science, particularly in the treatment of muscle wasting and degenerative disorders. With a total of 7 patents, his work has the potential to impact many lives.
Latest Patents
One of his latest patents is a method for treating muscle wasting syndrome using antagonist antibodies against GDF-8. This patent discloses novel molecules related to growth and differentiation factor-8 (GDF-8), including mouse and humanized antibodies and antibody fragments. These molecules inhibit GDF-8 activity and signaling both in vitro and in vivo. The patent also outlines methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative disorders of muscle, bone, and insulin metabolism, particularly amyotrophic lateral sclerosis (ALS). Additionally, it provides pharmaceutical compositions for treating such disorders using the antibodies, polypeptides, polynucleotides, and vectors of the invention.
Another significant patent by Pangalos is a method for treating sarcopenia using antagonist antibodies against GDF-8. Similar to his previous patent, this disclosure provides novel molecules related to GDF-8 and outlines methods for addressing degenerative disorders, including ALS. The pharmaceutical compositions described in this patent also utilize the innovative antibodies and related components.
Career Highlights
Throughout his career, Menelas N Pangalos has worked with prominent organizations such as Wyeth and the University of Pennsylvania. His experience in these institutions has allowed him to develop groundbreaking research and innovative solutions in the medical field.
Collaborations
Pangalos has collaborated with notable individuals in his field, including Frank S Walsh and Margaret Maria Zaleska. These collaborations have contributed to the advancement of his research and the development of his patents.
Conclusion
Menelas N Pangalos is a distinguished inventor whose work in the treatment of muscle and bone health has led to significant advancements in medical science. His innovative patents and collaborations highlight his commitment to improving health outcomes for individuals suffering from degenerative disorders.