Company Filing History:
Years Active: 2009-2012
Title: **Inventor Profile: Mei Geng from Bedford, MA**
Introduction
Mei Geng is a notable inventor based in Bedford, Massachusetts, recognized for his significant contributions to the field of protein production. With a total of two patents to his name, he is making strides in the application of genetically-engineered cells for enhanced protein yield, which holds promise for various biotechnological advancements.
Latest Patents
One of Mei Geng's latest inventions is a system and method for protein production, which focuses on employing genetically-engineered animal or plant cells with modified protein folding or processing capacities. This innovative approach features genetically-engineered cells that incorporate one or more recombinant expression cassettes. These cassettes encode a protein of interest and a polypeptide functional in the unfolded protein response (UPR) pathway of the cells. Notably, the co-expression of this polypeptide significantly enhances the yield of the protein of interest. In one implementation, the genetically-engineered cells are animal cells, with the co-expressed polypeptide playing a role as a component or modulator of an XBP1- or ATF6-mediated UPR pathway. This invention reflects the growing trend of utilizing genetic engineering for improving protein production processes.
Career Highlights
Mei Geng is currently associated with Wyeth, a leading biopharmaceutical company, where he applies his expertise in protein production. Throughout his career, he has contributed to various projects that leverage cutting-edge biotechnological techniques, enhancing the company's innovative capabilities in the life sciences sector.
Collaborations
In his work, Mei Geng collaborates closely with co-workers Yijie Gao and Nicole M Piche. These partnerships are instrumental in advancing their shared goals within the company and promoting innovations in protein research and production.
Conclusion
Mei Geng's notable patents and collaborations underscore his impact on the field of biotechnology. His innovative approaches to enhancing protein production through genetically-engineered cells may pave the way for future advances in therapeutic development and biotechnological applications. As he continues to work with talented individuals at Wyeth, his contributions will likely remain influential in the life sciences arena.