Location History:
- Wilmington, DE (US) (1999 - 2001)
- San Diego, CA (US) (2014)
Company Filing History:
Years Active: 1999-2014
Title: Innovations and Contributions of Mehran F Moghaddam
Introduction
Mehran F Moghaddam is a notable inventor based in San Diego, CA. He has made significant contributions to the field of medicinal chemistry, particularly in the development of compounds that target epoxide hydrolases for therapeutic applications. With a total of 3 patents, his work has the potential to impact the treatment of various inflammatory diseases.
Latest Patents
One of his latest patents focuses on inhibitors of epoxide hydrolases for the treatment of inflammation. This invention provides compounds that inhibit epoxide hydrolase, which can be utilized in therapeutic applications for treating hypertension. The preferred class of compounds has a specific structure where Z can be oxygen or sulfur, W can be carbon, phosphorus, or sulfur, and X and Y can independently be nitrogen, oxygen, or sulfur. Additionally, X can further be carbon, with various configurations for R and R' based on the elements present.
Another significant patent by Moghaddam details methods of treating inflammatory diseases mediated by poly-unsaturated lipid metabolites through the inhibition of epoxide hydrolase. This patent also includes methods for assaying or screening epoxide hydrolase inhibitors for specificity and toxicity, along with novel biologically active tetrahydrofuran diols derived from arachidonic acid.
Career Highlights
Throughout his career, Mehran F Moghaddam has worked with esteemed institutions such as the University of California and Signal Pharmaceuticals, Inc. His research has contributed to advancements in understanding and treating inflammatory conditions, showcasing his expertise in the field.
Collaborations
Moghaddam has collaborated with notable individuals in his field, including Bruce D Hammock and Babak Borhan. These collaborations have likely enhanced the scope and impact of his research endeavors.
Conclusion
Mehran F Moghaddam's innovative work in the field of medicinal chemistry, particularly regarding epoxide hydrolase inhibitors, demonstrates his commitment to advancing therapeutic options for inflammatory diseases. His contributions are significant and continue to influence the scientific community.