Location History:
- Toride, JP (2005 - 2006)
- Osaka, JP (2008)
Company Filing History:
Years Active: 2005-2008
Title: Mayako Yamazaki: Innovator in Biochemical Research
Introduction
Mayako Yamazaki is a prominent inventor based in Toride, Japan. She has made significant contributions to the field of biochemical research, particularly in the development of methods for evaluating phosphatase inhibitors and understanding amyloid-β protein aggregation. With a total of 3 patents, her work has implications for treating neurodegenerative disorders.
Latest Patents
Yamazaki's latest patents include innovative methods for evaluating phosphatase inhibitors. One of her notable inventions identifies OVARC1000473 (SEQ ID NO: 1) and NT2RM1000377 (SEQ ID NO: 3) as clones that suppress CREB activation by forskolin. This invention provides evaluation methods using these genes and the proteins they encode. Furthermore, these proteins have been found to enhance cell damage. The compounds screened based on these evaluation methods are useful as agents for inhibiting the CREB dephosphorylation reaction and for preventing and treating memory disorders and neurodegenerative disorders. Another significant patent focuses on amyloid-β protein aggregation-regulating factors. This invention provides proteins that suppress or promote the aggregation of amyloid-β protein, along with polynucleotides encoding these proteins. It also includes a method for screening compounds that regulate the aggregation of amyloid-β protein, which can lead to therapeutic agents for treating or preventing Alzheimer's disease.
Career Highlights
Throughout her career, Mayako Yamazaki has worked with notable companies in the pharmaceutical industry, including Fujisawa Pharmaceutical Company, Ltd. and Astellas Pharma GmbH. Her experience in these organizations has contributed to her expertise in biochemical research and innovation.
Collaborations
Yamazaki has collaborated with esteemed colleagues such as Susumu Satoh and Hiroyuki Arakawa. These collaborations have further enriched her research and development efforts in the field.
Conclusion
Mayako Yamazaki is a distinguished inventor whose work in biochemical research has the potential to impact the treatment of neurodegenerative disorders. Her innovative patents and collaborations highlight her significant contributions to science and medicine.