Mauro Biffoni

Title: Mauro Biffoni: Innovator in Monoclonal Antibodies and Gene Therapy

Introduction

Mauro Biffoni is a prominent inventor based in Rome, Italy. He has made significant contributions to the fields of monoclonal antibodies and gene therapy. With a total of 2 patents, his work focuses on innovative medical solutions that address critical health challenges.

Latest Patents

Biffoni's latest patents include a groundbreaking monoclonal antibody targeting FGFR4. This patent details the use of these antibodies as medicaments and diagnostic agents, specifically binding to the acid box domain of FGFR4. The disclosure also encompasses nucleic acids coding for the antibody, vectors, host cells for expression, antibody-drug conjugates, and pharmaceutical compositions. Additionally, he has developed methods for preventing graft rejection in transplantation using a newly discovered protein, LAG-3. This method allows for the transplantation of engineered cells without general immunosuppression, maintaining the host's immune system functionality.

Career Highlights

Throughout his career, Mauro Biffoni has worked with notable companies such as Applied Research Systems Ars Holding N.V. and Exiris S.r.l. His innovative approaches have positioned him as a key figure in the development of therapeutic solutions.

Collaborations

Biffoni has collaborated with esteemed colleagues, including Ruben Papoian and Paola Gallinari. These partnerships have further enhanced his research and development efforts in the medical field.

Conclusion

Mauro Biffoni's contributions to monoclonal antibodies and gene therapy exemplify his commitment to advancing medical science. His innovative patents and collaborations highlight his role as a leading inventor in the industry.