Location History:
- Beverly, MA (US) (1998)
- Newburyport, MA (US) (2013)
Company Filing History:
Years Active: 1998-2013
Title: The Innovations of Maurice W. Southworth
Introduction
Maurice W. Southworth is a notable inventor based in Newburyport, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of methods and compositions for protein expression. With a total of 3 patents to his name, Southworth's work has implications for various applications in research and industry.
Latest Patents
One of Southworth's latest patents is focused on the expression of toxic genes in vivo in a non-natural host. This invention provides compositions and methods for expressing a toxic protein in a host cell, preferably a bacterial host cell. The host cell contains at least one T7 RNA polymerase gene on its chromosome, along with one or more genes encoding a T7 RNA polymerase inhibitor located on an F' plasmid or on the chromosome.
Another significant patent involves modified proteins comprising controllable intervening protein sequences (CIVPS). This invention is directed towards modified proteins and methods of their production. The modified proteins include a CIVPS inserted into or adjacent to a target protein, which can be excised or cleaved under predetermined conditions. This technology has potential applications in the purification of target proteins through a one-step protocol.
Career Highlights
Maurice W. Southworth is currently associated with New England Biolabs, Inc., a company known for its innovative contributions to the life sciences. His work at this organization has allowed him to further his research and development efforts in biotechnology.
Collaborations
Some of Southworth's notable coworkers include Francine B. Perler and Donald G. Comb. Their collaborative efforts have likely contributed to the advancements in the projects they have worked on together.
Conclusion
Maurice W. Southworth's contributions to biotechnology through his patents and work at New England Biolabs, Inc. highlight his innovative spirit and dedication to advancing scientific knowledge. His inventions have the potential to impact various fields, making him a significant figure in the realm of biotechnology.