Company Filing History:
Years Active: 2011
Title: Maureen Costello: Innovator in Nucleic Acid Technology
Introduction
Maureen Costello is a prominent inventor based in Beachwood, OH (US). She has made significant contributions to the field of nucleic acid technology, particularly through her innovative patent. Her work focuses on enhancing the stability and efficacy of compacted nucleic acids, which are crucial for various biomedical applications.
Latest Patents
Maureen holds a patent for "Lyophilizable and enhanced compacted nucleic acids." This invention addresses how counterions of polycations used to compact nucleic acids can profoundly affect the shape and stability of the particles formed. The shape of these particles is associated with differential serum nuclease resistance and colloidal stability. A key aspect of her research is the turbidity parameter, which serves as a surrogate for determining these properties. Additionally, her work highlights how counterions, such as acetate, can protect compacted nucleic acid complexes from the adverse effects of lyophilization.
Career Highlights
Maureen is currently associated with Copernicus Therapeutics, Inc., where she continues to advance her research in nucleic acid technologies. Her innovative approach has positioned her as a leader in her field, contributing to the development of effective transfection methods for delivering nucleic acids into mammalian cells.
Collaborations
Maureen collaborates with notable colleagues, including Mark J Cooper and Murali Krishna Pasumarthy. Their combined expertise enhances the research and development efforts at Copernicus Therapeutics, Inc.
Conclusion
Maureen Costello's contributions to nucleic acid technology exemplify the impact of innovative research in the biomedical field. Her patent and ongoing work continue to pave the way for advancements in therapeutic applications.