This inventor holds 3 USPTO granted patents and 1 published patent application, plus 1 CIPO patent and 1 EPO patent. Top assignee: European Molecular Biology Laboratory. Active years: 2003-2024.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2003-2024
Title: Matthias W. Hentze: Innovator in RNA Biology
Introduction
Matthias W. Hentze is a prominent inventor based in Heidelberg, Germany, known for his groundbreaking contributions to the field of RNA biology. With a total of three patents to his name, Hentze has significantly advanced our understanding of RNA-binding proteins and their implications in various diseases.
Latest Patents
Hentze's latest patents include the following:
1. Enhanced RNA Interactome Capture (eRIC) - This invention pertains to an improved method for detecting RNA-binding proteins (RBPs) in cells, tissues, or organisms, utilizing oligonucleotides that incorporate locked nucleic acid (LNA) nucleotide analogues.
2. Modulators of Vault RNAs for Use in the Treatment of Diseases - This patent focuses on the association of vault RNAs (vtRNA) with p62, a key player in cellular autophagy. The invention provides a novel strategy for modulating the binding of vtRNA to p62, offering potential therapeutic avenues for diseases linked to impaired autophagy, such as cancer and neurodegenerative disorders. Additionally, it outlines methods for screening new therapeutic compounds that influence autophagy through the p62/vtRNA axis.
Career Highlights
Hentze has held positions at leading research institutions, notably the European Molecular Biology Laboratory (EMBL). His work at EMBL has established him as a key figure in molecular biology, particularly in RNA research.
Collaborations
Throughout his career, Hentze has collaborated with various esteemed professionals in his field, including Efrosyni Paraskeva and Joel Ignazio Perez-Perri. These partnerships have contributed to significant advancements in the understanding of RNA dynamics.
Conclusion
Matthias W. Hentze's innovative work in RNA biology, encapsulated in his patents and collaborations, underscores his impact on the scientific community. As research continues to evolve, his contributions will undoubtedly play a crucial role in developing new therapeutic strategies for diseases linked to RNA and autophagy.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile