Location History:
- Mainz-Kastel, DE (2016)
- Mainz, DE (2017)
Company Filing History:
1 out of 14 
1 out of 44 
Years Active: 2016-2017
Title: Innovations of Matthias Theobald in Antigen Recognizing Constructs
Introduction
Matthias Theobald is a notable inventor based in Mainz, Germany. He has made significant contributions to the field of antigen recognizing constructs, particularly through his innovative patents. With a total of 2 patents, his work focuses on enhancing the functionality and stability of single-chain antigen recognizing constructs (scARCs).
Latest Patents
Theobald's latest patents include groundbreaking inventions. One of his patents is titled "Single chain antigen recognizing constructs (scARCs) stabilized by the introduction of novel disulfide bonds." This invention relates to a scARC composed of stabilized variable domains, which prevents mis-pairing with endogenous ARC chains. The patent also discloses methods for designing and producing cells that express the scARC, along with nucleic acids and pharmaceutical compositions for therapeutic applications in cancer and infectious diseases.
Another significant patent is "Method for improving the specific effector function of single-chain antigen-recognizing genetic constructs (scARC) through murinization thereof." This invention outlines a method for producing a cell line that expresses a stabilized functional scARC. It involves co-expression of genetic constructs that contain murine amino acid exchanges, enhancing the T-cell response against tumor-associated peptide antigens.
Career Highlights
Matthias Theobald has worked at prestigious institutions, including Universitätsmedizin der Johannes Gutenberg-Universität Mainz and Johannes Gutenberg-Universität Mainz. His research has significantly advanced the understanding and application of scARCs in therapeutic contexts.
Collaborations
Theobald has collaborated with notable colleagues, including Ralf-Holger Voss and Shao-An Xue. These collaborations have contributed to the development and refinement of his innovative constructs.
Conclusion
Matthias Theobald's contributions to the field of antigen recognizing constructs demonstrate his commitment to advancing medical science. His patents reflect a deep understanding of protein engineering and its potential applications in therapy.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.