Company Filing History:
6 out of 75 
2 out of 1,975 
Years Active: 2019-2025
Title: Matthias Friedrich: Innovator in Bispecific Antibody Constructs
Introduction
Matthias Friedrich is a prominent inventor based in Munich, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of bispecific antibody constructs. With a total of six patents to his name, Friedrich's work is at the forefront of medical innovation.
Latest Patents
Friedrich's latest patents include groundbreaking inventions such as the PSMA and CD3 bispecific T cell engaging antibody constructs. This invention provides bispecific antibody constructs characterized by a first domain binding to PSMA, a second domain binding to an extracellular epitope of the human CD3ε chain, and a third domain that is a specific Fc modality. Additionally, the invention encompasses a polynucleotide encoding the antibody construct, a vector containing this polynucleotide, host cells expressing the construct, and a pharmaceutical composition comprising the same. Another notable patent is the optimized cross-species specific bispecific single chain antibody constructs. This invention features a bispecific single chain antibody construct that binds to a target cell surface antigen via a first binding domain and to the T cell surface antigen CD3 via a second binding domain, with serum albumin fused to the C-terminus of the antibody construct. It also includes a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide, and a host cell transformed or transfected with said vector.
Career Highlights
Throughout his career, Matthias Friedrich has worked with leading companies in the biotechnology sector, including Amgen Research (Munich) GmbH and Amgen Inc. His expertise in antibody constructs has positioned him as a key player in the development of innovative therapeutic solutions.
Collaborations
Friedrich has collaborated with notable colleagues such as Tobias Raum and Markus Münz. These partnerships have further enhanced his research and development efforts in the field of bispecific antibodies.
Conclusion
Matthias Friedrich's contributions to the field of biotechnology, particularly in bispecific antibody constructs, demonstrate his innovative spirit and commitment to advancing medical science. His patents reflect a deep understanding of complex biological interactions and hold promise for future therapeutic applications.