The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Feb. 02, 2017
Amgen Research (Munich) Gmbh, Munich, DE;
Tobias Raum, Munich, DE;
Markus Münz, Munich, DE;
Johannes Brozy, Munich, DE;
Peter Kufer, Munich, DE;
Patrick Hoffmann, Munich, DE;
Matthias Friedrich, Munich, DE;
Benno Rattel, Munich, DE;
Pamela Bogner, Munich, DE;
Andreas Wolf, Munich, DE;
Cornelius Pompe, Munich, DE;
AMGEN RESEARCH (MUNICH) GMBH, Munich, DE;
Abstract
The present invention provides bispecific antibody constructs of a specific Fc modality characterized by comprising a first domain binding to a target cell surface antigen, a second domain binding to an extracellular epitope of the human and/or theCD3ε chain and a third domain, which is the specific Fc modality. Moreover, the invention provides a polynucleotide, encoding the antibody construct, a vector comprising this polynucleotide, host cells, expressing the construct and a pharmaceutical composition comprising the same.