Cambridge, MA, United States of America

Matthew G Stanton

USPTO Granted Patents = 3 

 

Average Co-Inventor Count = 2.9

ph-index = 1


Company Filing History:


Years Active: 2025

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3 patents (USPTO):Explore Patents

Title: Matthew G. Stanton: Innovator in DNA Vector Technology

Introduction

Matthew G. Stanton is a prominent inventor based in Cambridge, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of DNA vectors. With a total of 3 patents to his name, Stanton's work focuses on innovative methods for gene delivery and expression.

Latest Patents

Stanton's latest patents include groundbreaking technologies such as "Closed-ended DNA vectors obtainable from cell-free synthesis and process for obtaining ceDNA vectors." This application describes methods for synthetic synthesis and cell-free synthesis of DNA vectors, specifically closed-ended DNA vectors (e.g., ceDNA vectors) that possess a linear and continuous structure for the delivery and expression of transgenes. The invention outlines an in vitro process for producing these closed-ended DNA vectors, along with the corresponding DNA vector products and their applications. The methods ensure that the DNA vectors produced are free from unwanted contaminants typically introduced during production in cell lines, such as bacterial or insect cell lines.

Another notable patent is related to "Lipids and compositions thereof." This patent provides details on lipids characterized by specific formulas and their pharmaceutically acceptable salts. It also discusses lipid nanoparticle (LNP) compositions that incorporate these lipids and a capsid-free, non-viral vector, such as ceDNA. These LNPs are designed for targeted delivery of DNA vectors to specific sites, including cells, tissues, and organs.

Career Highlights

Matthew G. Stanton is currently associated with Generation Bio Co., where he continues to advance his research in DNA vector technology. His work has positioned him as a key figure in the biotechnology sector, contributing to innovative solutions for gene therapy and related applications.

Collaborations

Stanton collaborates with notable colleagues, including Birte Nolting and Andrew Milstead. Their combined expertise enhances the research and development efforts at Generation Bio Co.

Conclusion

Matthew G. Stanton's contributions to the field of biotechnology, particularly in the area of DNA vectors, highlight his innovative spirit and dedication to advancing genetic research. His patents reflect a commitment to improving gene delivery methods, which could have significant implications for therapeutic applications.

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