Company Filing History:
Years Active: 2002-2015
Title: Matteo Ghirri: Innovator in Pharmaceutical Crystallization
Introduction
Matteo Ghirri is a notable inventor based in Milan, Italy. He has made significant contributions to the field of pharmaceutical sciences, particularly in the area of crystalline forms of compounds. With a total of 3 patents to his name, Ghirri's work has implications for drug development and formulation.
Latest Patents
One of Ghirri's latest patents involves the crystalline forms of 6-(1H-imidazol-1-yl)-2-phenylquinazoline. This invention relates to the solid state of the compound and includes novel crystalline forms of the base, as well as pharmaceutically acceptable salts and solvates. The patent also details methods for preparing these forms, their respective pharmaceutical formulations, and therapeutic uses. The compound can be obtained as the free base in five different crystalline forms, including three polymorphic forms and two hydrates.
Another significant patent is for a crystalline and stable form of Andolast disodium salt. This new crystalline Form A is triclinic and displays a thermal event at 98-112°C, melting with decomposition at about 400°C. Notably, Andolast disodium Form A is a non-hygroscopic solid, which is surprisingly stable under various humidity conditions. This stability allows for consistency and reproducibility in both chemical and pharmaceutical manufacturing processes, making it more viable and cost-effective compared to highly hygroscopic solids.
Career Highlights
Throughout his career, Matteo Ghirri has worked with prominent companies in the pharmaceutical industry, including Rottapharm Spa and Eurand International S.p.a. His expertise in crystallization and solid-state chemistry has positioned him as a valuable asset in the development of new pharmaceutical products.
Collaborations
Ghirri has collaborated with notable professionals in his field, including Antonio Giordani and Lucio C Rovati. These collaborations have further enhanced his research and development efforts in pharmaceutical sciences.
Conclusion
Matteo Ghirri's innovative work in the field of pharmaceutical crystallization has led to significant advancements in drug formulation and stability. His contributions are essential for the ongoing development of effective pharmaceutical products.