Location History:
- Täby, SE (2003 - 2004)
- Uppsala, SE (2003 - 2004)
Company Filing History:
Years Active: 2003-2004
Title: The Innovations of Mathias Uhlén
Introduction
Mathias Uhlén is a prominent inventor based in Täby, Sweden. He has made significant contributions to the field of biotechnology, particularly in the development of methods for affinity separation and novel bacterial receptor structures. With a total of four patents to his name, Uhlén's work has had a substantial impact on various applications in the life sciences.
Latest Patents
Uhlén's latest patents include a method of affinity separation that utilizes immobilized proteinaceous ligands, specifically focusing on the modification of asparagine residues to enhance stability. Another notable patent describes methods for creating stabilized combinatorial proteins by modifying Asn residues and randomizing protein molecules to alter their binding characteristics. Additionally, he has developed novel proteins through mutagenesis of surface-exposed amino acids in natural bacterial receptors, ensuring that these proteins maintain their basic structure and stability.
Career Highlights
Throughout his career, Uhlén has worked with several notable companies, including Biovitrum AB and Affibody AB. His expertise in protein engineering and affinity separation has positioned him as a leader in his field. Uhlén's innovative approaches have paved the way for advancements in therapeutic applications and diagnostic tools.
Collaborations
Uhlén has collaborated with esteemed colleagues such as Per-Åke Nygren and Björn M Nilsson. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and the development of groundbreaking technologies.
Conclusion
Mathias Uhlén's contributions to biotechnology through his patents and collaborations highlight his role as a key innovator in the field. His work continues to influence advancements in protein engineering and affinity separation techniques.